Choosing the right audio interface with MIDI ports can make a small studio feel much more connected, responsive, and reliable. The best models balance clean audio, stable drivers, and the right I/O for your setup.
Below, we focus on practical picks for musicians, producers, streamers, and podcasters who want simple recording today with room to grow tomorrow.
Best 10 Audio Interface with Midi Ports Picks for 2026
Studio-Ready 4x4 Hub
- 4-in/4-out USB-C interface with MIDI I/O
- Two mic preamps plus hardware monitoring
- Loopback and LCD screen for easy workflow
Best For: Small studios and podcasters who need MIDI I/O and low-latency monitoring
Budget Recording Starter
PreSonus AudioBox 96 25th Anniversary
- 2-channel interface with MIDI I/O
- Bus-powered USB 2.0 for portable recording
- Includes Studio One Artist and Ableton Live Lite
Best For: Beginners who want a budget-friendly, portable interface with MIDI support
Simple MIDI Link Cable
- 1 in/1 out MIDI cable with indicator lights
- Plug-and-play for Windows, Mac, and iPad
- Low-latency transmission with built-in driver support
Best For: Players who need a simple USB-C MIDI connection for keyboards and synths
Feature-Packed Studio Hub
Focusrite Scarlett 4i4 4th Gen
- 4-in/4-out interface with MIDI I/O
- Two mic preamps, Hi-Z inputs, and four line inputs
- Auto Gain, Clip Safe, and Air mode
Best For: Home studios and producers needing flexible inputs and MIDI support
Portable MIDI-Ready Recording
- MIDI I/O with 2-in/2-out recording
- Two Onyx preamps with 48V phantom power
- Bus-powered USB 2.0 with direct monitoring
Best For: Musicians and mobile recordists who want a compact MIDI interface
Simple Starter Interface
- Two combo inputs with phantom power
- Zero-latency monitoring with USB/Direct switch
- Includes MPC Beats software
Best For: Beginners who want an easy 2-channel interface for recording and streaming
High-Channel MIDI Studio Interface
- 4x4 USB audio/MIDI interface with one MIDI I/O
- 24-bit/192kHz recording and four MIDAS preamps
- Metal chassis built for durability
Best For: Home studios and musicians needing four channels plus MIDI
Studio-Ready Compact Interface
2x2 24-bit/192kHz USB-C Audio Interface
- Plug-and-play USB-C setup on Mac and PC
- 24-bit/192kHz recording with two combo inputs
- Direct monitoring, phantom power, and Hi-Z support
Best For: Portable home recording for vocals, guitar, and laptop creators
Flexible Monitoring Pick
USB C Interface With 3 Monitoring Modes
- Stereo, Mix, and USB monitoring modes
- XLR/6.35mm input support with phantom power
- Compact, portable design for recording and streaming
Best For: Podcasts, streaming, and quick recording setups
Creator-Friendly Choice
PS22 Lite USB Audio Interface for PC
- 24-bit/192kHz recording with 106dB dynamic range
- Dedicated instrument input plus 48V phantom power
- ProStudio routing software with loopback support
Best For: Beginners and creators who record vocals, guitar, and streams
Studio-Ready 4×4 Hub – MOTU M4 USB-C Audio Interface
If you want an audio interface with midi ports that also handles everyday recording jobs well, the MOTU M4 is a strong all-around pick. It offers 4-in/4-out USB-C connectivity, two microphone preamps, loopback, hardware monitoring, and a clear LCD screen, making it useful for tracking, mixing, and podcasting on Mac, PC, or iOS hardware.
Best For: Creators who want a compact 4×4 interface with MIDI I/O, low-latency monitoring, and loopback for flexible recording.
Pros:
- 4-in/4-out USB-C design with MIDI I/O
- Two microphone preamps for basic studio recording
- Hardware monitoring and loopback support
- Up to 192 kHz sample rate
Cons:
- No bundled operating system is included
- Only two mic preamps, so larger sessions may need more inputs
The M4 stands out as a practical desktop interface when you need MIDI connectivity plus straightforward recording tools in a compact unit. Its combination of monitoring features, multiple outputs, and included content makes it especially appealing for small studios and podcasters.
Budget Recording Starter – PreSonus AudioBox 96 25th Anniversary
The PreSonus AudioBox 96 is a value-focused audio interface with midi ports for musicians who want a simple, portable setup. It includes two Class-A mic preamps, two instrument inputs, MIDI I/O, and bus-powered USB 2.0 operation, so it fits well for home recording, guitar tracking, and mobile use.
Best For: Beginners and portable recordists who want an affordable 2-channel interface with MIDI connectivity and bundled software.
Pros:
- Includes MIDI I/O alongside two mic preamps
- Bus-powered USB 2.0 design for mobile use
- Supports up to 24-bit/96 kHz recording and playback
- Comes with Studio One Artist, Ableton Live Lite, and Studio Magic Plug-In Suite
Cons:
- Only two channels, so it is limited for larger setups
- USB 2.0 is less modern than USB-C interfaces
This interface is a sensible entry point if you mainly need a compact recording box with MIDI support. The included software bundle adds a lot of value, and the zero-latency mixer control is helpful when you want a simple monitoring setup.
Simple MIDI Link Cable – LEKATO USB-C MIDI Interface
If you specifically need an audio interface with midi ports for connecting a keyboard, synth, or drum pad to a computer, the LEKATO cable keeps the setup simple. It provides 1 in and 1 out, supports up to 16 channels, and is designed for fast, stable MIDI transmission on Windows, Mac, and compatible iPad setups.
Best For: Musicians who need a plug-and-play USB-C MIDI connection rather than a full audio interface.
Pros:
- 1 in/1 out MIDI interface with indicators for easier troubleshooting
- Plug-and-play operation with built-in driver support
- Compatible with Windows, macOS, and iPad use cases
- Low-latency transmission with EMI-resistant design
Cons:
- It is a MIDI cable, not a full audio interface
- Only supports standard MIDI setups, so compatibility should be checked first
This is the most straightforward option in the group if your priority is just MIDI connectivity. It is a practical utility cable for editing and recording MIDI data, but it does not replace a multichannel audio interface.
Feature-Packed Studio Hub – Focusrite Scarlett 4i4 4th Gen
The Focusrite Scarlett 4i4 4th Gen is a strong audio interface with midi ports for musicians building a flexible desktop setup. It gives you two 4th Gen mic preamps, two Hi-Z instrument inputs, four line inputs, four line outputs, and MIDI I/O, along with modern extras like Auto Gain, Clip Safe, and Air mode.
Best For: Home studios and producers who want a 4-in/4-out interface with MIDI I/O and helpful recording features.
Pros:
- 4-in/4-out layout with MIDI I/O
- Two mic preamps, two Hi-Z inputs, and four line inputs
- Auto Gain and Clip Safe help avoid bad levels
- 120 dB dynamic range and 24-bit/192 kHz support
Cons:
- More expensive than basic 2-channel beginner interfaces
- Best feature set may be more than casual users need
For a versatile modern setup, the Scarlett 4i4 offers a lot of connectivity in a compact form. Its combination of MIDI support, multiple inputs and outputs, and recording safeguards makes it especially useful when you want room to expand.
Portable MIDI-Ready Recording – Mackie Onyx Producer 2X2
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonIf you want an audio interface with midi ports that keeps the setup simple, the Mackie Onyx Producer 2X2 is a compact 2-in/2-out option with 24-bit/192kHz recording. It pairs MIDI I/O with two Onyx mic preamps, bus-powered USB 2.0 operation, and direct monitoring for straightforward home or mobile sessions.
Best For: Musicians and mobile recordists who want a bus-powered interface with MIDI I/O and clean preamps.
Pros:
- Includes MIDI I/O alongside 2-in/2-out USB audio recording
- Two Onyx mic preamps with 48V phantom power for condenser mics
- Zero-latency direct monitoring with dedicated monitor outputs
- Bus-powered design helps keep the setup portable
Cons:
- Only 2 input and 2 output channels
- Best suited to small recording setups rather than larger studio rigs
This is a practical pick if your priority is MIDI support plus clean analog recording in a compact box. The included plugins and instruments add extra value for users who want to get started quickly.
Simple Starter Interface – M-AUDIO M-Track Duo
The M-AUDIO M-Track Duo is a straightforward USB audio interface if you need a compact recording tool rather than a full audio interface with midi ports. It focuses on two combo inputs, 48kHz audio, transparent preamps, and easy zero-latency monitoring for podcasts, vocals, guitar, and livestreams.
Best For: Beginners and creators who want a simple 2-channel interface for recording, streaming, or podcasting.
Pros:
- Two combo XLR/Line/Instrument inputs with phantom power
- USB/Direct monitoring switch for zero-latency listening
- Compact portable design for Mac or PC use
- Includes MPC Beats software for production starters
Cons:
- No MIDI ports listed in the supplied specifications
- 48kHz maximum sample rate is lower than some higher-end interfaces
This is a good value-oriented interface for basic recording tasks, but it is not the right choice if MIDI connectivity is a must-have. Its strength is ease of use for vocals, guitar, and streaming.
High-Channel MIDI Studio Interface – Behringer UMC404HD
If you need an audio interface with midi ports for a larger recording setup, the Behringer UMC404HD offers 4×4 USB 2.0 connectivity and 24-bit/192kHz resolution. It adds one MIDI I/O pair, four MIDAS-designed mic preamps, and a metal chassis for users who want more inputs and outputs than a basic starter interface.
Best For: Home studios and musicians who need four channels plus MIDI connectivity for more flexible recording.
Pros:
- 4×4 USB audio/MIDI interface with one MIDI I/O
- 24-bit/192kHz audio for high-resolution recording
- Four MIDAS-designed mic preamps with +48V phantom power
- Metal chassis is built for durability
Cons:
- Bulkier than compact 2-channel interfaces
- Windows operating system is listed in the supplied details
This model stands out when you want more routing flexibility and MIDI support in the same unit. It is the most capable pick here for users who expect to expand beyond a simple two-input setup.
Studio-Ready Compact Interface – 2×2 24-bit/192kHz USB-C Audio Interface
If you want an audio interface with midi ports, this compact 2×2 unit is worth a look for basic recording setups that prioritize clean sound, USB-C convenience, and portable use. It offers class-compliant plug-and-play operation on Mac and PC, plus 24-bit/192kHz recording for higher-resolution sessions.
Best For: Solo creators, laptop users, and home studios that need a portable USB-C interface for vocals, guitar, and simple recording workflows.
Pros:
- 24-bit/192kHz conversion for detailed, low-noise recording
- USB-C bus power with no drivers required for Mac and PC
- Two combo inputs with 48V phantom power and Hi-Z support
- Direct monitoring plus 3.5mm headphone connectivity
Cons:
- No MIDI ports are listed in the supplied specifications
- Only 2 input channels, so it is not built for larger sessions
- Best suited to straightforward setups rather than multi-device rigs
This is a practical pick if your priority is a small, reliable interface with strong audio specs and easy setup. The fixed LED gain rings and loopback/monitor mix features make it especially friendly for creators who want simplicity without giving up recording quality.
Flexible Monitoring Pick – USB C Interface With 3 Monitoring Modes
For buyers comparing an audio interface with midi ports, this 2×2 USB-C model stands out for its monitoring tools and compact design, though MIDI connectivity is not listed in the supplied details. It focuses on clear recording, easy switching, and broad device compatibility for music, streaming, and podcasting.
Best For: Streamers, podcasters, and mobile creators who want simple monitoring controls and a portable 2-channel interface.
Pros:
- Three monitoring modes: Stereo, Mix, and USB
- 24-bit recording with a dedicated audio chip to reduce latency
- XLR/6.35mm input support with 48V phantom power
- Lightweight design with included cables and adapter
Cons:
- No MIDI ports are mentioned in the product information
- Maximum sample rate is 48kHz, lower than some studio-focused models
- Drivers may benefit from a third-party ASIO install for best results
This interface is appealing if you want fast setup and monitoring flexibility more than advanced routing. The LED level indicators and multiple input options make it easy to keep sessions under control, especially for live use and casual recording.
Creator-Friendly Choice – PS22 Lite USB Audio Interface for PC
If you are shopping for an audio interface with midi ports, the MAONO PS22 Lite is a strong compact option for recording and streaming, but the supplied notes do not list MIDI connectivity. What it does offer is high-resolution 24-bit/192kHz recording, a dedicated instrument input, and software routing tools that make it useful for creators who switch between vocals, guitar, and live broadcast work.
Best For: Beginners, streamers, and home recordists who want an easy-to-use interface with strong vocal and guitar features.
Pros:
- 24-bit/192kHz recording with 106dB dynamic range
- Dedicated instrument input with adjustable impedance for guitar
- 48V phantom power and up to 56dB preamp gain for microphones
- ProStudio routing software with virtual channels and loopback support
Cons:
- No MIDI ports are specified in the product details
- Only 2 channels, so it is geared toward smaller setups
- Best results depend on selecting the MAONO ASIO driver in software
This is a sensible all-around choice if you want an interface that is easy to learn but still offers useful creator features. Its compact size, monitoring controls, and flexible software support make it a good fit for everyday recording and streaming tasks.
How We Picked the Best Audio Interface with Midi Ports
We prioritized Audio Interface with Midi Ports options that offer dependable connectivity, solid preamps, sensible input/output layouts, and features that matter in real studios, not just spec sheets. We also considered compatibility with common DAWs, monitoring flexibility, and whether each unit suits beginners or more advanced home-recording workflows.
Quick Comparison
At a high level, the best choice depends on your source count and workflow. Compact 2×2 interfaces work well for solo recording, while 4×4 models are better for multi-source sessions and more complex routing. If you use keyboards, synths, or drum machines, MIDI input and output can be a deciding factor. USB-C models generally offer simpler modern connectivity, but the most important detail is stable performance with your computer and software.
Key Buying Factors for an Audio Interface with Midi Ports
I/O Count and Routing
Look at how many microphones, instruments, and line-level devices you need to record at once. An Audio Interface with Midi Ports should still meet your audio needs first, because MIDI support is only useful if the analog inputs and outputs fit your workflow.
Preamp Quality and Gain
Clean preamps matter for vocals, acoustic instruments, and dynamic microphones. If you plan to use gain-hungry mics, choose a model known for strong, quiet amplification.
MIDI Connectivity
Check whether the unit provides traditional 5-pin MIDI in/out or requires a separate USB MIDI solution. Traditional ports are often more convenient for hardware synths, sequencers, and older gear.
Monitoring and Latency
Direct monitoring, low-latency drivers, and reliable software control can make recording far easier. This is especially important if you track vocals or live instruments while hearing yourself in real time.
Compatibility and Power
Make sure the interface works with your computer, tablet, or mobile setup if you plan to move between devices. Some users will also value bus-powered convenience, while others prefer external power for more robust routing.
Who Should Buy Which Audio Interface with Midi Ports?
Beginners and solo creators usually do best with a simple 2×2 interface that keeps setup fast and affordable. Home producers who use external synths or controllers should lean toward an Audio Interface with Midi Ports and more flexible routing. If you record multiple sources at once, step up to a 4×4 model for added headroom and connectivity. Streamers and podcasters may prefer the easiest monitoring layout and the most straightforward driver support, even if they do not need every advanced feature.
In short, choose the smallest interface that fully supports your current workflow, then add MIDI and extra I/O only when you truly need them.